Ontology highlight
ABSTRACT:
SUBMITTER: Dong T
PROVIDER: S-EPMC4349212 | biostudies-literature | 2014 Mar
REPOSITORIES: biostudies-literature
Dong Tuochuan T Kang Le L Hutson Alan A Xiong Chengjie C Tian Lili L
Biometrical journal. Biometrische Zeitschrift 20131122 2
Although most of the statistical methods for diagnostic studies focus on disease processes with binary disease status, many diseases can be naturally classified into three ordinal diagnostic categories, that is normal, early stage, and fully diseased. For such diseases, the volume under the ROC surface (VUS) is the most commonly used index of diagnostic accuracy. Because the early disease stage is most likely the optimal time window for therapeutic intervention, the sensitivity to the early dise ...[more]