Ontology highlight
ABSTRACT:
SUBMITTER: Adkins I
PROVIDER: S-EPMC4352954 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Adkins Irena I Fucikova Jitka J Garg Abhishek D AD Agostinis Patrizia P Špíšek Radek R
Oncoimmunology 20141201 12
The concept of immunogenic cancer cell death (ICD), as originally observed during the treatment with several chemotherapeutics or ionizing irradiation, has revolutionized the view on the development of new anticancer therapies. ICD is defined by endoplasmic reticulum (ER) stress response, reactive oxygen species (ROS) generation, emission of danger-associated molecular patterns and induction of antitumor immunity. Here we describe known and emerging cancer cell death-inducing physical modalities ...[more]