Ontology highlight
ABSTRACT:
SUBMITTER: Tschernig T
PROVIDER: S-EPMC4355561 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Tschernig Thomas T Hartwig Christina C Jeron Andreas A Dinh Quoc Thai QT Gereke Marcus M Bruder Dunja D
International journal of genomics 20150224
Asthma is the consequence of allergic inflammation in the lung compartments and lung-draining lymph nodes. Dendritic cells initiate and promote T cell response and drive it to immunity or allergy. However, their modes of action during asthma are poorly understood. In this study, an allergic inflammation with ovalbumin was induced in 38 mice versus 42 control animals. After ovalbumin aerosol challenge, conventional dendritic cells (CD11c/MHCII/CD8) were isolated from the lungs and the draining ly ...[more]