Ontology highlight
ABSTRACT:
SUBMITTER: Im H
PROVIDER: S-EPMC4356947 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Im Hyungsoon H Shao Huilin H Park Yong Il YI Peterson Vanessa M VM Castro Cesar M CM Weissleder Ralph R Lee Hakho H
Nature biotechnology 20140420 5
Exosomes show potential for cancer diagnostics because they transport molecular contents of the cells from which they originate. Detection and molecular profiling of exosomes is technically challenging and often requires extensive sample purification and labeling. Here we describe a label-free, high-throughput approach for quantitative analysis of exosomes. Our nano-plasmonic exosome (nPLEX) assay is based on transmission surface plasmon resonance through periodic nanohole arrays. Each array is ...[more]