Ontology highlight
ABSTRACT:
SUBMITTER: Kajikawa M
PROVIDER: S-EPMC4357444 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Kajikawa Masataka M Kinohira Seiko S Ando Akira A Shimoyama Miki M Kato Misako M Fukuzawa Hideya H
PloS one 20150312 3
Several microalgae accumulate high levels of squalene, and as such provide a potentially valuable source of this useful compound. However, the molecular mechanism of squalene biosynthesis in microalgae is still largely unknown. We obtained the sequences of two enzymes involved in squalene synthesis and metabolism, squalene synthase (CrSQS) and squalene epoxidase (CrSQE), from the model green alga Chlamydomonas reinhardtii. CrSQS was functionally characterized by expression in Escherichia coli an ...[more]