Ontology highlight
ABSTRACT:
SUBMITTER: Kogo R
PROVIDER: S-EPMC4359219 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
Kogo Ryunosuke R How Christine C Chaudary Naz N Bruce Jeff J Shi Wei W Hill Richard P RP Zahedi Payam P Yip Kenneth W KW Liu Fei-Fei FF
Oncotarget 20150101 2
Cervical cancer is the third most common cancer in women worldwide. In the present study, global microRNA profiling for 79 cervical cancer patient samples led to the identification of miR-218 down-regulation in cervical cancer tissues compared to normal cervical tissues. Lower miR-218 expression was associated significantly with worse overall survival (OS), disease-free survival (DFS), and pelvic/aortic lymph node recurrence. In vitro, miR-218 over-expression decreased clonogenicity, migration, ...[more]