Ontology highlight
ABSTRACT:
SUBMITTER: Knief U
PROVIDER: S-EPMC4359978 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Knief U U Hemmrich-Stanisak G G Wittig M M Franke A A Griffith S C SC Kempenaers B B Forstmeier W W
Heredity 20150114 4
Most molecular measures of inbreeding do not measure inbreeding at the scale that is most relevant for understanding inbreeding depression-namely the proportion of the genome that is identical-by-descent (IBD). The inbreeding coefficient FPed obtained from pedigrees is a valuable estimator of IBD, but pedigrees are not always available, and cannot capture inbreeding loops that reach back in time further than the pedigree. We here propose a molecular approach to quantify the realized proportion o ...[more]