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Synthesis of the furo[2,3-b]chromene ring system of hyperaspindols A and B.

ABSTRACT: The synthesis of the unique furo[2,3-b]chromene ring system found in hyperaspidinols A and B, acylphloroglucinols from Hypericum chinense has been achieved in twelve steps. By comparison of the NMR spectra of the synthesized compounds with those of the natural products, a relative stereochemistry is suggested, especially that of the ketal carbon.

SUBMITTER: Paterson DL

PROVIDER: S-EPMC4362291 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature

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Synthesis of the furo[2,3-b]chromene ring system of hyperaspindols A and B.

Paterson Danielle L DL Barker David D

Beilstein journal of organic chemistry 20150217

The synthesis of the unique furo[2,3-b]chromene ring system found in hyperaspidinols A and B, acylphloroglucinols from Hypericum chinense has been achieved in twelve steps. By comparison of the NMR spectra of the synthesized compounds with those of the natural products, a relative stereochemistry is suggested, especially that of the ketal carbon. ...[more]

PMID: 25815078

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