Ontology highlight
ABSTRACT:
SUBMITTER: Carnesecchi J
PROVIDER: S-EPMC4363467 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Carnesecchi Julie J Malbouyres Marilyne M de Mets Richard R Balland Martial M Beauchef Gallic G Vié Katell K Chamot Christophe C Lionnet Claire C Ruggiero Florence F Vanacker Jean-Marc JM
PloS one 20150317 3
The post-menopausal decrease in estrogen circulating levels results in rapid skin deterioration pointing out to a protective effect exerted by these hormones. The identity of the skin cell type responding to estrogens is unclear as are the cellular and molecular processes they elicit. Here, we reported that lack of estrogens induces rapid re-organization of the human dermal fibroblast cytoskeleton resulting in striking cell shape change. This morphological change was accompanied by a spatial re- ...[more]