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Recent developments in vascular imaging techniques in tissue engineering and regenerative medicine.


ABSTRACT: Adequate vascularisation is key in determining the clinical outcome of stem cells and engineered tissue in regenerative medicine. Numerous imaging modalities have been developed and used for the visualization of vascularisation in tissue engineering. In this review, we briefly discuss the very recent advances aiming at high performance imaging of vasculature. We classify the vascular imaging modalities into three major groups: nonoptical methods (X-ray, magnetic resonance, ultrasound, and positron emission imaging), optical methods (optical coherence, fluorescence, multiphoton, and laser speckle imaging), and hybrid methods (photoacoustic imaging). We then summarize the strengths and challenges of these methods for preclinical and clinical applications.

SUBMITTER: Upputuri PK 

PROVIDER: S-EPMC4363824 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature

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Recent developments in vascular imaging techniques in tissue engineering and regenerative medicine.

Upputuri Paul Kumar PK   Sivasubramanian Kathyayini K   Mark Chong Seow Khoon CS   Pramanik Manojit M  

BioMed research international 20150302


Adequate vascularisation is key in determining the clinical outcome of stem cells and engineered tissue in regenerative medicine. Numerous imaging modalities have been developed and used for the visualization of vascularisation in tissue engineering. In this review, we briefly discuss the very recent advances aiming at high performance imaging of vasculature. We classify the vascular imaging modalities into three major groups: nonoptical methods (X-ray, magnetic resonance, ultrasound, and positr  ...[more]

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