Dataset Information

Associations of neighborhood area level deprivation with the metabolic syndrome and inflammation among middle- and older- age adults.

ABSTRACT:

Background

The study examines the association of neighborhood socioeconomic deprivation and metabolic syndrome with inflammation.

Methods

The analysis included 19, 079 black and white participants from the REasons for Geographic And Racial Differences in Stroke Study who were age > 45 years at baseline. Logistic regression examined whether neighborhood deprivation was associated with increased odds of METS and CRP-MetS.

Results

Among black adults, residing in the most deprived neighborhoods was associated with increased odds of obesity (p < .01), lower HDL (p < .001), high blood pressure (p < .01), elevated fasting glucose (p < .001), inflammation (p < .01), and CRP-MetS (p < .001). Among white adults, neighborhood deprivation was associated with higher waist circumference (p < .001), lower HDL (p < .001), higher triglycerides (p < .01), higher glucose (p < .001), higher BMI (p < .0001), higher blood pressure (p = .01), METS (p < .001), inflammation (p < .01) and CRP-MetS (p < .001).

Conclusions

These findings highlight the role of neighborhood socioeconomic deprivation on METS and CRP-MetS for black and white adults. Interventions tailored to address the contextual effects of deprived neighborhoods may reduce the observed neighborhood disparities.

SUBMITTER: Keita AD

PROVIDER: S-EPMC4364504 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature

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Publications

Associations of neighborhood area level deprivation with the metabolic syndrome and inflammation among middle- and older- age adults.

Keita Akilah Dulin AD Judd Suzanne E SE Howard Virginia J VJ Carson April P AP Ard Jamy D JD Fernandez Jose R JR

BMC public health 20141223

<h4>Background</h4>The study examines the association of neighborhood socioeconomic deprivation and metabolic syndrome with inflammation.<h4>Methods</h4>The analysis included 19, 079 black and white participants from the REasons for Geographic And Racial Differences in Stroke Study who were age > 45 years at baseline. Logistic regression examined whether neighborhood deprivation was associated with increased odds of METS and CRP-MetS.<h4>Results</h4>Among black adults, residing in the most depri ...[more]

PMID: 25539758

Similar Datasets

Project description:OBJECTIVES:Two processes generate total variance in age at death: heterogeneity (between-group variance) and individual stochasticity (within-group variance). Limited research has evaluated how these two components have changed over time. We quantify the degree to which area-level deprivation contributed to total variance in age at death in Scotland between 1981 and 2011. DESIGN:Full population and mortality data for Scotland were obtained and matched with the Carstairs score, a standardised z-score calculated for each part-postcode sector that measures relative area-level deprivation. A z-score above zero indicates that the part-postcode sector experienced higher deprivation than the national average. A z-score below zero indicates lower deprivation. From the aggregated data we constructed 40 lifetables, one for each deprivation quintile in 1981, 1991, 2001 and 2011 stratified by sex. PRIMARY OUTCOME MEASURES:Total variance in age at death and the proportion explained by area-level deprivation heterogeneity (between-group variance). RESULTS:The most deprived areas experienced stagnating or slightly increasing variance in age at death. The least deprived areas experienced decreasing variance. For males, the most deprived quintile life expectancy was between 7% and 11% lower and the SD is between 6% and 25% higher than the least deprived. This suggests that the effect of deprivation on the SD of longevity is comparable to its effect on life expectancy. Decomposition analysis revealed that contributions from between-group variance doubled between 1981 and 2011 but at most only explained 4% of total variance. CONCLUSIONS:This study adds to the emerging body of literature demonstrating that socio-economic groups have experienced diverging trends in variance in age at death. The contribution from area-level deprivation to total variance in age at death, which we were able to capture, has doubled since 1981. Area-level deprivation may play an increasingly important role in mortality inequalities.

Dataset Information

Associations of neighborhood area level deprivation with the metabolic syndrome and inflammation among middle- and older- age adults.

Background

Methods

Results

Conclusions

Publications

Associations of neighborhood area level deprivation with the metabolic syndrome and inflammation among middle- and older- age adults.

Similar Datasets

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