A network of RNA and protein interactions in Fronto Temporal Dementia.
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ABSTRACT:
SUBMITTER: Fontana F
PROVIDER: S-EPMC4365750 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
A network of RNA and protein interactions in Fronto Temporal Dementia.
Fontana Francesca F Siva Kavitha K Denti Michela A MA
Frontiers in molecular neuroscience 20150319
Frontotemporal dementia (FTD) is a neurodegenerative disorder characterized by degeneration of the fronto temporal lobes and abnormal protein inclusions. It exhibits a broad clinicopathological spectrum and has been linked to mutations in seven different genes. We will provide a picture, which connects the products of these genes, albeit diverse in nature and function, in a network. Despite the paucity of information available for some of these genes, we believe that RNA processing and post-tran ...[more]
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