Ontology highlight
ABSTRACT:
SUBMITTER: Konno Y
PROVIDER: S-EPMC4366258 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Konno Yasunori Y Ueki Shigeharu S Takeda Masahide M Kobayashi Yoshiki Y Tamaki Mami M Moritoki Yuki Y Oyamada Hajime H Itoga Masamichi M Kayaba Hiroyuki H Omokawa Ayumi A Hirokawa Makoto M
PloS one 20150319 3
Recent evidence has shown that eosinophils play an important role in metabolic homeostasis through Th2 cytokine production. GPR120 (FFA4) is a G protein-coupled receptor (GPCR) for long-chain fatty acids that functions as a regulator of physiological energy metabolism. In the present study, we aimed to investigate whether human eosinophils express GPR120 and, if present, whether it possesses a functional capacity on eosinophils. Eosinophils isolated from peripheral venous blood expressed GPR120 ...[more]