Ontology highlight
ABSTRACT:
SUBMITTER: Saravanan KM
PROVIDER: S-EPMC4367036 | biostudies-literature | 2015 Jan-Jun
REPOSITORIES: biostudies-literature
Saravanan Konda Mani KM Selvaraj Samuel S
Journal of natural science, biology, and medicine 20150101 1
In our study, we have concluded that two proteins with 88% homology choose different energetically favorable pathways in the very early stage of the folding process to attain their native folds. Subsequent reports from other investigators by performing folding and unfolding kinetics experiments concur with our findings. We herewith discuss the key papers revealing computational and experimental analysis of two designed proteins with similar sequence distant folds. Further we suggest that the the ...[more]