Ontology highlight
ABSTRACT:
SUBMITTER: Rivera PD
PROVIDER: S-EPMC4368452 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Rivera Phillip D PD Raghavan Ramya K RK Yun Sanghee S Latchney Sarah E SE McGovern Mary-Katherin MK García Emily F EF Birnbaum Shari G SG Eisch Amelia J AJ
Hippocampus 20150313 4
Addiction has been proposed to emerge from associations between the drug and the reward-associated contexts. This associative learning has a cellular correlate, as there are more cFos+ neurons in the hippocampal dentate gyrus (DG) after psychostimulant conditioned place preference (CPP) versus saline controls. However, it is unknown whether morphine CPP leads to a similar DG activation, or whether DG activation is due to locomotion, handling, pharmacological effects, or-as data from contextual f ...[more]