Ontology highlight
ABSTRACT:
SUBMITTER: Vagnini LD
PROVIDER: S-EPMC4368621 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Vagnini Laura Diniz LD Renzi Adriana A Oliveira-Pelegrin Gabriela Ravanelli GR Canas Maria do Carmo Tomitão Mdo C Petersen Claudia Guilhermino CG Mauri Ana Lucia AL Oliveira João Batista Alcantara JB Baruffi Ricardo Luiz Razera RL Cavagna Mario M Franco Junior José Gonçalves JG
PloS one 20150320 3
It's known that the members of the TP53 family are involved in the regulation of female reproduction. Studies in mice showed that the TP73 gene (member of this family) plays a role in the size of follicular pool, ovulation rate and maintenance of genomic stability. In the present study we analyzed data from 605 patients with ≤ 37 years attending their first intracytoplasmic sperm injection (ICSI). The association between the TP73 polymorphism (rs4648551, A>G) and the following parameters related ...[more]