Unity in diversity: shared mechanism of entry among paramyxoviruses.
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ABSTRACT:
SUBMITTER: Palgen JL
PROVIDER: S-EPMC4369139 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
Unity in diversity: shared mechanism of entry among paramyxoviruses.
Palgen Jean-Louis JL Jurgens Eric M EM Moscona Anne A Porotto Matteo M Palermo Laura M LM
Progress in molecular biology and translational science 20141201
The Paramyxoviridae family includes many viruses that are pathogenic in humans, including parainfluenza viruses, measles virus, respiratory syncytial virus, and the emerging zoonotic Henipaviruses. No effective treatments are currently available for these viruses, and there is a need for efficient antiviral therapies. Paramyxoviruses enter the target cell by binding to a cell surface receptor and then fusing the viral envelope with the target cell membrane, allowing the release of the viral geno ...[more]
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