Ontology highlight
ABSTRACT:
SUBMITTER: Swaminathan S
PROVIDER: S-EPMC4369320 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
Swaminathan Sundararaman S Rosner Mitchell H MH Okusa Mark D MD
Seminars in nephrology 20150101 1
Sepsis-associated acute kidney injury (SA-AKI) is linked to high morbidity and mortality. To date, singular approaches to target specific pathways known to contribute to the pathogenesis of SA-AKI have failed. Because of the complexity of the pathogenesis of SA-AKI, a reassessment necessitates integrative approaches to therapeutics of SA-AKI that include general supportive therapies such as the use of vasopressors, fluids, antimicrobials, and target-specific and time-dependent therapeutics. Ther ...[more]