Ontology highlight
ABSTRACT:
SUBMITTER: Tian Q
PROVIDER: S-EPMC4369426 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Tian Qu Q Glynn Nancy W NW Erickson Kirk I KI Aizenstein Howard J HJ Simonsick Eleanor M EM Yaffe Kristine K Harris Tamara B TB Kritchevsky Stephen B SB Boudreau Robert M RM Newman Anne B AB Lopez Oscar L OL Saxton Judith J Rosano Caterina C Rosano Caterina C
Behavioural brain research 20150202
The neuroprotective effects of physical activity (PA) are consistently shown in older adults, but the neural substrates, particularly in white matter (WM), are understudied, especially in very old adults with the fastest growth rate and the highest risk of dementia. This study quantified the association between PA and WM integrity in adults over 80. The moderating effects of cardiometabolic conditions, physical functional limitations and WM hyperintensities were also examined, as they can affect ...[more]