Sustained Aeration of Infant Lungs (SAIL) trial: study protocol for a randomized controlled trial.
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ABSTRACT:
SUBMITTER: Foglia EE
PROVIDER: S-EPMC4372179 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
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Sustained Aeration of Infant Lungs (SAIL) trial: study protocol for a randomized controlled trial.
Foglia Elizabeth E EE Owen Louise S LS Thio Marta M Ratcliffe Sarah J SJ Lista Gianluca G Te Pas Arjan A Hummler Helmut H Nadkarni Vinay V Ades Anne A Posencheg Michael M Keszler Martin M Davis Peter P Kirpalani Haresh H
Trials 20150315
<h4>Background</h4>Extremely preterm infants require assistance recruiting the lung to establish a functional residual capacity after birth. Sustained inflation (SI) combined with positive end expiratory pressure (PEEP) may be a superior method of aerating the lung compared with intermittent positive pressure ventilation (IPPV) with PEEP in extremely preterm infants. The Sustained Aeration of Infant Lungs (SAIL) trial was designed to study this question.<h4>Methods/design</h4>This multisite pros ...[more]
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