Ontology highlight
ABSTRACT:
SUBMITTER: Baltazar LM
PROVIDER: S-EPMC4372525 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Baltazar Ludmila Matos LM Krausz Aimee E AE Souza Ana Camila Oliveira AC Adler Brandon L BL Landriscina Angelo A Musaev Tagai T Nosanchuk Joshua D JD Friedman Adam J AJ
PloS one 20150324 3
Antimicrobial photodynamic inhibition (aPI) utilizes radical stress generated from the excitation of a photosensitizer (PS) with light to destroy pathogens. Its use against Trichophyton rubrum, a dermatophytic fungus with increasing incidence and resistance, has not been well characterized. Our aim was to evaluate the mechanism of action of aPI against T. rubrum using curcumin as the PS in both free and nanoparticle (curc-np) form. Nanocarriers stabilize curcumin and allow for enhanced solubilit ...[more]