Ontology highlight
ABSTRACT:
SUBMITTER: Ritch R
PROVIDER: S-EPMC4372533 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Ritch Robert R Darbro Ben B Menon Geeta G Khanna Cheryl L CL Solivan-Timpe Frances F Roos Ben R BR Sarfarzi Mansoor M Kawase Kazuhide K Yamamoto Tetsuya T Robin Alan L AL Lotery Andrew J AJ Fingert John H JH
JAMA ophthalmology 20140501 5
<h4>Importance</h4>Normal-tension glaucoma (NTG) is a common cause of vision loss.<h4>Objective</h4>To investigate the role of TANK binding kinase 1 (TBK1) gene duplications in NTG to gain insights into the causes of glaucoma that occurs at low intraocular pressure (IOP).<h4>Design, setting, and participants</h4>In this multicenter case-control study, we investigated patients who met the criteria for NTG, including glaucomatous optic neuropathy, visual field defects, and maximum recorded untreat ...[more]