Ontology highlight
ABSTRACT:
SUBMITTER: Mayshar Y
PROVIDER: S-EPMC4373338 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Mayshar Yoav Y Yanuka Ofra O Benvenisty Nissim N
Journal of cellular and molecular medicine 20100617 6
Teratogens are substances that may cause defects in normal embryonic development while not necessarily being toxic in adults. Identification of possible teratogenic compounds has been historically beset by the species-specific nature of the teratogen response. To examine teratogenic effects on early human development we performed non-biased expression profiling of differentiating human embryonic and induced pluripotent stem cells treated with several drugs--ethanol, lithium, retinoic acid (RA), ...[more]