Characterization of resistance to rhabdovirus and retrovirus infection in a human myeloid cell line.
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ABSTRACT:
SUBMITTER: Boso G
PROVIDER: S-EPMC4374779 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
Characterization of resistance to rhabdovirus and retrovirus infection in a human myeloid cell line.
Boso Guney G Somia Nikunj V NV
PloS one 20150326 3
Viruses interact with various permissive and restrictive factors in host cells throughout their replication cycle. Cell lines that are non-permissive to viral infection have been particularly useful in discovering host cell proteins involved in viral life cycles. Here we describe the characterization of a human myeloid leukemia cell line, KG-1, that is resistant to infection by retroviruses and a Rhabdovirus. We show that KG-1 cells are resistant to infection by Vesicular Stomatits Virus as well ...[more]
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