Ontology highlight
ABSTRACT:
SUBMITTER: Rietveld CA
PROVIDER: S-EPMC4375246 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
Rietveld Cornelius A CA Conley Dalton D Eriksson Nicholas N Esko Tõnu T Medland Sarah E SE Vinkhuyzen Anna A E AA Yang Jian J Boardman Jason D JD Chabris Christopher F CF Dawes Christopher T CT Domingue Benjamin W BW Hinds David A DA Johannesson Magnus M Kiefer Amy K AK Laibson David D Magnusson Patrik K E PK Mountain Joanna L JL Oskarsson Sven S Rostapshova Olga O Teumer Alexander A Tung Joyce Y JY Visscher Peter M PM Benjamin Daniel J DJ Cesarini David D Koellinger Philipp D PD
Psychological science 20141006 11
A recent genome-wide-association study of educational attainment identified three single-nucleotide polymorphisms (SNPs) whose associations, despite their small effect sizes (each R (2) ≈ 0.02%), reached genome-wide significance (p < 5 × 10(-8)) in a large discovery sample and were replicated in an independent sample (p < .05). The study also reported associations between educational attainment and indices of SNPs called "polygenic scores." In three studies, we evaluated the robustness of these ...[more]