Ontology highlight
ABSTRACT:
SUBMITTER: He F
PROVIDER: S-EPMC4375784 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
He Feng F Wei Chuanxian C Wu Honggang H Cheung David D Jiao Renjie R Ma Jun J
Nature communications 20150326
Tissue expansion and patterning are integral to development; however, it is unknown quantitatively how a mother accumulates molecular resources to invest in the future of instructing robust embryonic patterning. Here we develop a model, Tissue Expansion-Modulated Maternal Morphogen Scaling (TEM(3)S), to study scaled anterior-posterior patterning in Drosophila embryos. Using both ovaries and embryos, we measure a core quantity of the model, the scaling power of the Bicoid (Bcd) morphogen gradient ...[more]