Ontology highlight
ABSTRACT:
SUBMITTER: Asnani M
PROVIDER: S-EPMC4376133 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Asnani Mukta M Kumar Parimal P Hellen Christopher U T CU
Virology 20150227
Picornavirus genomes contain internal ribosomal entry sites (IRESs) that promote end-independent translation initiation. Five structural classes of picornavirus IRES have been identified, but numerous IRESs remain unclassified. Here, previously unrecognized Type IV IRESs were identified in members of three proposed picornavirus genera (Limnipivirus, Pasivirus, Rafivirus) and four recognized genera (Kobuvirus, Megrivirus, Sapelovirus, Parechovirus). These IRESs are ~230-420 nucleotides long, refl ...[more]