Ontology highlight
ABSTRACT:
SUBMITTER: Zhang Z
PROVIDER: S-EPMC4376716 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Zhang Zhichun Z Tian Hua H Lv Ping P Wang Weiping W Jia Zhuqing Z Wang Sainan S Zhou Chunyan C Gao Xuejun X
PloS one 20150327 3
Mutation of distal-less homeobox 3 (DLX3) is responsible for human tricho-dento-osseous syndrome (TDO) with amelogenesis imperfecta, indicating a crucial role of DLX3 in amelogenesis. However, the expression pattern of DLX3 and its specific function in amelogenesis remain largely unknown. The aim of this study was to investigate the effects of DLX3 on enamel matrix protein (EMP) genes. By immunohistochemistry assays of mouse tooth germs, stronger immunostaining of DLX3 protein was identified in ...[more]