Ontology highlight
ABSTRACT:
SUBMITTER: Kempen PJ
PROVIDER: S-EPMC4377731 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Theranostics 20150301 6
Increasing cell survival in stem cell therapy is an important challenge for the field of regenerative medicine. Here, we report theranostic mesoporous silica nanoparticles that can increase cell survival through both diagnostic and therapeutic approaches. First, the nanoparticle offers ultrasound and MRI signal to guide implantation into the peri-infarct zone and away from the most necrotic tissue. Second, the nanoparticle serves as a slow release reservoir of insulin-like growth factor (IGF)-a ...[more]