Ontology highlight
ABSTRACT:
SUBMITTER: Tycowski KT
PROVIDER: S-EPMC4378190 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Tycowski Kazimierz T KT Guo Yang Eric YE Lee Nara N Moss Walter N WN Vallery Tenaya K TK Xie Mingyi M Steitz Joan A JA
Genes & development 20150301 6
Eukaryotic cells produce several classes of long and small noncoding RNA (ncRNA). Many DNA and RNA viruses synthesize their own ncRNAs. Like their host counterparts, viral ncRNAs associate with proteins that are essential for their stability, function, or both. Diverse biological roles--including the regulation of viral replication, viral persistence, host immune evasion, and cellular transformation--have been ascribed to viral ncRNAs. In this review, we focus on the multitude of functions playe ...[more]