Ontology highlight
ABSTRACT:
SUBMITTER: Mullen RD
PROVIDER: S-EPMC4378544 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Mullen Rachel D RD Behringer Richard R RR
Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation 20140712 5
The Müllerian duct (MD) forms the female reproductive tract (FRT) consisting of the oviducts, uterus, cervix, and upper vagina. FRT function is vital to fertility, providing the site of fertilization, embryo implantation and fetal development. Developmental defects in the formation and diseases of the FRT, including cancer and endometriosis, are prevalent in humans and can result in infertility and death. Furthermore, because the MDs are initially formed regardless of genotypic sex, mesenchymal ...[more]