Ontology highlight
ABSTRACT:
SUBMITTER: Chendamarai E
PROVIDER: S-EPMC4378855 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Chendamarai Ezhilarasi E Ganesan Saravanan S Alex Ansu Abu AA Kamath Vandana V Nair Sukesh C SC Nellickal Arun Jose AJ Janet Nancy Beryl NB Srivastava Vivi V Lakshmi Kavitha M KM Viswabandya Auro A Abraham Aby A Aiyaz Mohammed M Mullapudi Nandita N Mugasimangalam Raja R Padua Rose Ann RA Chomienne Christine C Chandy Mammen M Srivastava Alok A George Biju B Balasubramanian Poonkuzhali P Mathews Vikram V
PloS one 20150330 3
There is limited data on the clinical, cellular and molecular changes in relapsed acute promyeloytic leukemia (RAPL) in comparison with newly diagnosed cases (NAPL). We undertook a prospective study to compare NAPL and RAPL patients treated with arsenic trioxide (ATO) based regimens. 98 NAPL and 28 RAPL were enrolled in this study. RAPL patients had a significantly lower WBC count and higher platelet count at diagnosis. IC bleeds was significantly lower in RAPL cases (P=0.022). The ability of ma ...[more]