Ontology highlight
ABSTRACT:
SUBMITTER: McBee RM
PROVIDER: S-EPMC4379402 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
McBee Ross M RM Rozmiarek Shea A SA Meyerson Nicholas R NR Rowley Paul A PA Sawyer Sara L SL
Molecular biology and evolution 20150102 4
Over evolutionary time, both host- and virus-encoded genes have been continually selected to modify their interactions with one another. This has resulted in the rapid evolution of the specific codons that govern the physical interactions between host and virus proteins. Virologists have discovered that these evolutionary signatures, acquired in nature, can provide a shortcut in the functional dissection of host-virus interactions in the laboratory. However, the use of evolution studies in this ...[more]