Ontology highlight
ABSTRACT:
SUBMITTER: Wu Q
PROVIDER: S-EPMC4379480 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Wu Quan Q Cheng Zhongyi Z Zhu Jun J Xu Weiqing W Peng Xiaojun X Chen Chuangbin C Li Wenting W Wang Fengsong F Cao Lejie L Yi Xingling X Wu Zhiwei Z Li Jing J Fan Pingsheng P
Scientific reports 20150331
Suberoylanilide hydroxamic acid (SAHA) is a well-known histone deacetylase (HDAC) inhibitor and has been used as practical therapy for breast cancer and non-small cell lung cancer (NSCLC). It is previously demonstrated that SAHA treatment could extensively change the profile of acetylome and proteome in cancer cells. However, little is known about the impact of SAHA on other protein modifications and the crosstalks among different modifications and proteome, hindering the deep understanding of S ...[more]