Age differences in periventricular and deep white matter lesions.
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ABSTRACT:
SUBMITTER: Nyquist PA
PROVIDER: S-EPMC4380525 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Publications
Age differences in periventricular and deep white matter lesions.
Nyquist Paul A PA Bilgel Murat M Gottesman Rebecca R Yanek Lisa R LR Moy Taryn F TF Becker Lewis C LC Cuzzocreo Jennifer L JL Prince Jerry J Wasserman Bruce A BA Yousem David M DM Becker Diane M DM Kral Brian G BG Vaidya Dhananjay D
Neurobiology of aging 20150107 4
Deep white matter hyperintensity (DWMH) and periventricular (PV) white matter lesion volumes are associated with age and subsequent stroke. We studied age differences in these volumes accounting for collinearity and risk factors. Subjects were 563 healthy family members of early-onset coronary artery disease patients. Using 3T magnetic resonance imaging, lesions were classified as DWMH or PV. Age association with lesion classification was analyzed using random effects Tobit regression, adjusting ...[more]
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