Diversity in (p)ppGpp metabolism and effectors.
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ABSTRACT:
SUBMITTER: Liu K
PROVIDER: S-EPMC4380541 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Publications
Diversity in (p)ppGpp metabolism and effectors.
Liu Kuanqing K Bittner Alycia N AN Wang Jue D JD
Current opinion in microbiology 20150128
Bacteria produce guanosine tetraphosphate and pentaphosphate, collectively named (p)ppGpp, in response to a variety of environmental stimuli. These two remarkable molecules regulate many cellular processes, including the central dogma processes and metabolism, to ensure survival and adaptation. Work in Escherichia coli laid the foundation for understanding the molecular details of (p)ppGpp and its cellular functions. As recent studies expand to other species, it is apparent that there exists con ...[more]
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