Ontology highlight
ABSTRACT:
SUBMITTER: Normanno N
PROVIDER: S-EPMC4381449 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Normanno Nicola N Cree Ian A IA
BMC cancer 20150323
Molecularly defined subgroups of tumors characterized by specific driver mutations have been identified in the majority of cancers. The availability of novel drugs capable of targeting signaling pathways activated by genetic derangements has led to hypothesize the possibility to treat patients based on their genomic profile. A clear example is represented by lung adenocarcinoma for which it has been possible to identify driver genetic alterations in approximately 75% of the cases. Among these, R ...[more]