Ontology highlight
ABSTRACT:
SUBMITTER: Wang SJ
PROVIDER: S-EPMC4381592 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
Wang Shi-Jie SJ Cui Hong-Yong HY Liu Yan-Mei YM Zhao Pu P Zhang Yang Y Fu Zhi-Guang ZG Chen Zhi-Nan ZN Jiang Jian-Li JL
Oncotarget 20150101 1
Metastasis is considered a dynamic process in tumor development that is related to abnormal migration and invasion. Tumor cells can move as individual cells in two interconvertible modes: mesenchymal-type and amoeboid. Previously, we reported that the interaction between CD147 and Annexin II can inhibit the amoeboid movement in hepatocellular carcinoma (HCC) cells. However, the mechanism of CD147 involved in mesenchymal movement is still unclear. Notably, our results show overexpression of CD147 ...[more]