Ontology highlight
ABSTRACT:
SUBMITTER: Tsai CH
PROVIDER: S-EPMC4381593 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
Tsai Chun-Hao CH Tsai Hsiao-Chi HC Huang Ho-Ning HN Hung Chih-Hung CH Hsu Chin-Jung CJ Fong Yi-Chin YC Hsu Horng-Chaung HC Huang Yuan-Li YL Tang Chih-Hsin CH
Oncotarget 20150101 1
Resistin is a recently discovered adipocyte-secreting adipokine, which may play a critical role in modulating cancer pathogenesis. Chondrosarcoma is a highly malignant tumor known to frequently metastasize; however, the role of resistin in the metastasis of human chondrosarcoma is largely unknown. Here, we found that the expression of resistin was higher in chondrosarcoma biopsy tissues than in normal cartilage. Moreover, treatment with resistin increased matrix metalloproteinase (MMP)-2 express ...[more]