Ontology highlight
ABSTRACT:
SUBMITTER: Gallon L
PROVIDER: S-EPMC4382402 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Gallon Lorenzo L Traitanon Opas O Sustento-Reodica Nedjema N Leventhal Joseph J Ansari M Javeed MJ Gehrau Ricardo C RC Ariyamuthu Venkatesh V De Serres Sacha A SA Alvarado Antonio A Chhabra Darshika D Mathew James M JM Najafian Nader N Mas Valeria V
Kidney international 20141029 4
Tacrolimus and sirolimus are commonly used maintenance immunosuppressants in kidney transplantation. As their effects on immune cells and allograft molecular profiles have not been elucidated, we characterized the effects of tacrolimus to sirolimus conversion on the frequency and function of T cells, and on graft molecular profiles. Samples from renal transplant patients in a randomized trial of 18 patients with late sirolimus conversion and 12 on tacrolimus maintenance were utilized. Peripheral ...[more]