Dataset Information

A longitudinal cohort study of body mass index and childhood exposure to secondhand tobacco smoke and air pollution: the Southern California Children's Health Study.

ABSTRACT: BACKGROUND:Childhood body mass index (BMI) and obesity prevalence have been associated with exposure to secondhand smoke (SHS), maternal smoking during pregnancy, and vehicular air pollution. There has been little previous study of joint BMI effects of air pollution and tobacco smoke exposure. METHODS:Information on exposure to SHS and maternal smoking during pregnancy was collected on 3,318 participants at enrollment into the Southern California Children's Health Study. At study entry at average age of 10 years, residential near-roadway pollution exposure (NRP) was estimated based on a line source dispersion model accounting for traffic volume, proximity, and meteorology. Lifetime exposure to tobacco smoke was assessed by parent questionnaire. Associations with subsequent BMI growth trajectory based on annual measurements and attained BMI at 18 years of age were assessed using a multilevel modeling strategy. RESULTS:Maternal smoking during pregnancy was associated with estimated BMI growth over 8-year follow-up (0.72 kg/m2 higher; 95% CI: 0.14, 1.31) and attained BMI (1.14 kg/m2 higher; 95% CI: 0.66, 1.62). SHS exposure before enrollment was positively associated with BMI growth (0.81 kg/m2 higher; 95% CI: 0.36, 1.27) and attained BMI (1.23 kg/m2 higher; 95% CI: 0.86, 1.61). Growth and attained BMI increased with more smokers in the home. Compared with children without a history of SHS and NRP below the median, attained BMI was 0.80 kg/m2 higher (95% CI: 0.27, 1.32) with exposure to high NRP without SHS; 0.85 kg/m2 higher (95% CI: 0.43, 1.28) with low NRP and a history of SHS; and 2.15 kg/m2 higher (95% CI: 1.52, 2.77) with high NRP and a history of SHS (interaction p-value 0.007). These results suggest a synergistic effect. CONCLUSIONS:Our findings strengthen emerging evidence that exposure to tobacco smoke and NRP contribute to development of childhood obesity and suggest that combined exposures may have synergistic effects.

SUBMITTER: McConnell R

PROVIDER: S-EPMC4384197 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature

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A longitudinal cohort study of body mass index and childhood exposure to secondhand tobacco smoke and air pollution: the Southern California Children's Health Study.

McConnell Rob R Shen Ernest E Gilliland Frank D FD Jerrett Michael M Wolch Jennifer J Chang Chih-Chieh CC Lurmann Frederick F Berhane Kiros K

Environmental health perspectives 20141112 4

<h4>Background</h4>Childhood body mass index (BMI) and obesity prevalence have been associated with exposure to secondhand smoke (SHS), maternal smoking during pregnancy, and vehicular air pollution. There has been little previous study of joint BMI effects of air pollution and tobacco smoke exposure.<h4>Methods</h4>Information on exposure to SHS and maternal smoking during pregnancy was collected on 3,318 participants at enrollment into the Southern California Children's Health Study. At study ...[more]

PMID: 25389275

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Project description:An Environmental Justice (EJ) analysis was carried out using full Chemical Transport Models (CTMs) over Los Angeles, California, to determine how the combination of domain size and spatial resolution affects predicted air pollution disparities in present day and future simulations when data support from measurements is not available. One set of simulations used the Weather Research and Forecasting (WRF) model coupled with Chemistry (WRF/Chem) with spatial resolution ranging from 250 m to 36 km, comparable to census tract sizes, over domains ranging in size from 320 km2 to 10,000 km2. A second set of simulations used the UCD/CIT CTM with spatial resolution ranging from 4 km to 24 km over domains ranging in size from 98,000 km2 to 1,000,000 km2. Overall WRF/Chem model accuracy improved approximately 9% as spatial resolution increased from 4 km to 250 m in present-day simulations, with similar results expected for future simulations. Exposure disparity results are consistent with previous findings: the average Non-Hispanic White person in the study domain experiences PM2.5 mass concentrations 6–14% lower than the average resident, while the average Black and African American person experiences PM2.5 mass concentrations that are 3–22% higher than the average resident. Predicted exposure disparities were a function of the model configuration. Increasing the spatial resolution finer than approximately 1 km produced diminishing returns because the increased spatial resolution came at the expense of reduced domain size in order to maintain reasonable computational burden. Increasing domain size to capture regional trends, such as wealthier populations living in coastal areas, identified larger exposure disparities but the benefits were limited. CTM configurations that use spatial resolution/domain size of 1 km/103 km2 and 4 km/104 km2 over Los Angeles can detect a 0.5 μg m−3 exposure difference with statistical power greater than 90%. These configurations represent a balanced approach between statistical power, sensitivity across socio-economic groups, and computational burden when predicting current and future air pollution exposure disparities in Los Angeles. Air quality; Environmental disparity; PM2.5; Chemical transport model.

Project description:BackgroundAirports may represent significant sources of secondhand smoke (SHS) exposure for both travelers and employees. While previously common smoking rooms have largely disappeared from US airports, smoking continues to occur outdoors at terminal entrances. SHS may be especially high at arrival areas, since they oftentimes are partially enclosed by overhead departures, creating stagnant microenvironments. This study assessed particulate matter <2.5 microns in diameter (PM2.5), a common surrogate for SHS, at airport terminal locations to evaluate both outdoor exposure risk and possible indoor drift of SHS from outdoor sources.MethodsA convenience sample of nine airport terminal arrival areas in the US state of Florida was surveyed between February and July 2018. PM2.5 levels were assessed outdoors and indoors at terminal entrances and at control areas far into terminal interiors. We also examined the impact of smoking location on SHS exposure by correlating cigarette and passing vehicle counts with PM2.5 levels at terminals with contrasting proximity of designated smoking locations to terminal entrances.ResultsAlthough outdoor PM2.5 levels (mean 17.9, SD 6.1 µg/m3) were significantly higher than indoors (p < 0.001), there was no difference between indoor areas directly inside terminal entrances and areas much further interior (mean 8.8, SD 2.6 vs mean 8.5, SD 3.0 µg/m3, p=0.49). However, when smoking areas were in close proximity to terminal entrances, the number of lit cigarettes and vehicular traffic per minute predicted 70% of the variance of PM2.5 levels (p < 0.001), which was attributable mostly to the cigarette number (β = 0.83; 95% CI (0.55 to 1.11); p < 0.001). This effect was not observed at smoking areas further away.ConclusionPM2.5 data did not suggest indoor drift from outside smoking. Nevertheless, absolute exposure outdoors was high and correlated with the location of designated smoking areas. Further studies are needed to examine the effect of microclimate formation on exposure risk.

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Dataset Information

A longitudinal cohort study of body mass index and childhood exposure to secondhand tobacco smoke and air pollution: the Southern California Children's Health Study.

Publications

A longitudinal cohort study of body mass index and childhood exposure to secondhand tobacco smoke and air pollution: the Southern California Children's Health Study.

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