Occupational exposure to endocrine disruptors and lymphoma risk in a multi-centric European study.

ABSTRACT:

Background

Incidence rates of lymphoma are usually higher in men than in women, and oestrogens may protect against lymphoma.

Methods

We evaluated occupational exposure to endocrine disrupting chemicals (EDCs) among 2457 controls and 2178 incident lymphoma cases and subtypes from the European Epilymph study.

Results

Over 30 years of exposure to EDCs compared to no exposure was associated with a 24% increased risk of mature B-cell neoplasms (P-trend=0.02). Associations were observed among men, but not women.

Conclusions

Prolonged occupational exposure to endocrine disruptors seems to be moderately associated with some lymphoma subtypes.

SUBMITTER: Costas L 

PROVIDER: S-EPMC4385964 | biostudies-literature |

REPOSITORIES: biostudies-literature