Ontology highlight
ABSTRACT:
SUBMITTER: Herrer I
PROVIDER: S-EPMC4386080 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
BMC medical genomics 20150329
<h4>Background</h4>Ischemic cardiomyopathy (ICM) is characterized by transcriptomic changes that alter cellular processes leading to decreased cardiac output. Because the molecular network of ICM is largely unknown, the aim of this study was to characterize the role of new transcriptional regulators in the molecular mechanisms underlying the responses to ischemia.<h4>Methods</h4>Myocardial tissue explants from ICM patients and control (CNT) subjects were analyzed by RNA-Sequencing (RNA-Seq) and ...[more]