Ontology highlight
ABSTRACT:
SUBMITTER: Bagheri M
PROVIDER: S-EPMC4386084 | biostudies-literature | 2015 Apr-Jun
REPOSITORIES: biostudies-literature
Journal of reproduction & infertility 20150401 2
<h4>Background</h4>It has been demonstrated that insulin signaling pathway related genes have important roles in polycystic ovary syndrome (PCOS) risk. The goal of present investigation was to assess the potential association between INSR/NsiI (rs2059806) and INSR/PmlI (rs1799817) SNPs and PCOS.<h4>Methods</h4>50 women with PCOS and 47 normal controls entered the study. NsiI and PmlI SNPs in the INSR gene were determined by RFLP-PCR.<h4>Results</h4>INSR/NsiI (rs2059806) SNP GG, GA, AA, G and A g ...[more]