Ontology highlight
ABSTRACT:
SUBMITTER: Mazzone P
PROVIDER: S-EPMC4388727 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Mazzone Pellegrino P Scudiero Ivan I Ferravante Angela A Paolucci Marina M D'Andrea Luca E LE Varricchio Ettore E Telesio Gianluca G De Maio Chiara C Pizzulo Maddalena M Zotti Tiziana T Reale Carla C Vito Pasquale P Stilo Romania R
PloS one 20150407 4
The complexes formed by BCL10, MALT1 and specific members of the family of CARMA proteins (CBM complex), have recently focused much attention because they represent a central hub regulating activation of the transcription factor NF-κB following various cellular stimulations. In this manuscript, we report the functional characterization of a Danio rerio 241 amino acids polypeptide ortholog of the Caspase recruiting domain (CARD)-containing protein BCL10. Biochemical studies show that zebrafish Bc ...[more]