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Project INTEGRATE: An integrative study of brief alcohol interventions for college students.


ABSTRACT: This article provides an overview of a study that synthesizes multiple, independently collected alcohol intervention studies for college students into a single, multisite longitudinal data set. This research embraced innovative analytic strategies (i.e., integrative data analysis or meta-analysis using individual participant-level data), with the overall goal of answering research questions that are difficult to address in individual studies such as moderation analysis, while providing a built-in replication for the reported efficacy of brief motivational interventions for college students. Data were pooled across 24 intervention studies, of which 21 included a comparison or control condition and all included one or more treatment conditions. This yielded a sample of 12,630 participants (42% men; 58% first-year or incoming students). The majority of the sample identified as White (74%), with 12% Asian, 7% Hispanic, 2% Black, and 5% other/mixed ethnic groups. Participants were assessed 2 or more times from baseline up to 12 months, with varying assessment schedules across studies. This article describes how we combined individual participant-level data from multiple studies, and discusses the steps taken to develop commensurate measures across studies via harmonization and newly developed Markov chain Monte Carlo (MCMC) algorithms for 2-parameter logistic item response theory models and a generalized partial credit model. This innovative approach has intriguing promises, but significant barriers exist. To lower the barriers, there is a need to increase overlap in measures and timing of follow-up assessments across studies, better define treatment and control groups, and improve transparency and documentation in future single intervention studies.

SUBMITTER: Mun EY 

PROVIDER: S-EPMC4388772 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature

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Project INTEGRATE: An integrative study of brief alcohol interventions for college students.

Mun Eun-Young EY   de la Torre Jimmy J   Atkins David C DC   White Helene R HR   Ray Anne E AE   Kim Su-Young SY   Jiao Yang Y   Clarke Nickeisha N   Huo Yan Y   Larimer Mary E ME   Huh David D  

Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors 20141229 1


This article provides an overview of a study that synthesizes multiple, independently collected alcohol intervention studies for college students into a single, multisite longitudinal data set. This research embraced innovative analytic strategies (i.e., integrative data analysis or meta-analysis using individual participant-level data), with the overall goal of answering research questions that are difficult to address in individual studies such as moderation analysis, while providing a built-i  ...[more]

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2016-08-01 | GSE80559 | GEO