Ontology highlight
ABSTRACT:
SUBMITTER: Ferguson NM
PROVIDER: S-EPMC4390297 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Ferguson Neil M NM Kien Duong Thi Hue DT Clapham Hannah H Aguas Ricardo R Trung Vu Tuan VT Chau Tran Nguyen Bich TN Popovici Jean J Ryan Peter A PA O'Neill Scott L SL McGraw Elizabeth A EA Long Vo Thi VT Dui Le Thi le T Nguyen Hoa L HL Chau Nguyen Van Vinh NV Wills Bridget B Simmons Cameron P CP
Science translational medicine 20150301 279
Dengue is the most common arboviral infection of humans and is a public health burden in more than 100 countries. Aedes aegypti mosquitoes stably infected with strains of the intracellular bacterium Wolbachia are resistant to dengue virus (DENV) infection and are being tested in field trials. To mimic field conditions, we experimentally assessed the vector competence of A. aegypti carrying the Wolbachia strains wMel and wMelPop after challenge with viremic blood from dengue patients. We found th ...[more]