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Association of inpatient and outpatient glucose management with inpatient mortality among patients with and without diabetes at a major academic medical center.


ABSTRACT: Hospitalized patients with diabetes have experienced a disproportionate reduction in mortality over the past decade.To examine whether this differential decrease affected all patients with diabetes, and to identify explanatory factors.Serial, cross-sectional observational study.Academic medical center.All adult, nonobstetric patients with an inpatient discharge between January 1, 2000 and December 31, 2010.We assessed in-hospital mortality; inpatient glycemic control (percentage of hospital days with glucose below 70, above 299, and between 70 and 179 mg/dL, and standard deviation of glucose measurements), and outpatient glycemic control (hemoglobin A1c).We analyzed 322,938 admissions, including 76,758 (23.8%) with diabetes. Among 54,645 intensive care unit (ICU) admissions, there was a 7.8% relative reduction in the odds of mortality in each successive year for patients with diabetes, adjusted for age, race, payer, length of stay, discharge diagnosis, comorbidities, and service (odds ratio [OR]: 0.923, 95% confidence interval [CI]: 0.906-0.940). This was significantly greater than the 2.6% yearly reduction for those without diabetes (OR: 0.974, 95% CI: 0.963-0.985; P?

SUBMITTER: Butala NM 

PROVIDER: S-EPMC4390436 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature

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Association of inpatient and outpatient glucose management with inpatient mortality among patients with and without diabetes at a major academic medical center.

Butala Neel M NM   Johnson Benjamin K BK   Dziura James D JD   Reynolds Jesse S JS   Bozzo Janis E JE   Balcezak Thomas J TJ   Inzucchi Silvio E SE   Horwitz Leora I LI  

Journal of hospital medicine 20150128 4


<h4>Background</h4>Hospitalized patients with diabetes have experienced a disproportionate reduction in mortality over the past decade.<h4>Objective</h4>To examine whether this differential decrease affected all patients with diabetes, and to identify explanatory factors.<h4>Design</h4>Serial, cross-sectional observational study.<h4>Setting</h4>Academic medical center.<h4>Patients</h4>All adult, nonobstetric patients with an inpatient discharge between January 1, 2000 and December 31, 2010.<h4>M  ...[more]

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