Ontology highlight
ABSTRACT:
SUBMITTER: Scheffler K
PROVIDER: S-EPMC4395489 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Scheffler Kathleen K Minnes Refael R Fraisier Vincent V Paoletti Anne A Tran Phong T PT
The Journal of cell biology 20150401 1
Microtubules (MTs) and associated motors play a central role in nuclear migration, which is crucial for diverse biological functions including cell division, polarity, and sexual reproduction. In this paper, we report a dual mechanism underlying nuclear congression during fission yeast karyogamy upon mating of haploid cells. Using microfluidic chambers for long-term imaging, we captured the precise timing of nuclear congression and identified two minus end-directed motors operating in parallel i ...[more]