Ontology highlight
ABSTRACT:
SUBMITTER: Moon S
PROVIDER: S-EPMC4395893 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Moon Sanghoon S Keam Bhumsuk B Hwang Mi Yeong MY Lee Young Y Park Suyeon S Oh Ji Hee JH Kim Yeon-Jung YJ Lee Heun-Sik HS Kim Nam Hee NH Kim Young Jin YJ Kim Dong-Hyun DH Han Bok-Ghee BG Kim Bong-Jo BJ Lee Juyoung J
BMC musculoskeletal disorders 20150404
<h4>Background</h4>OA is a complex disease caused by environmental and genetic risk factors. The purpose of this study is to identify candidate copy number variations (CNVs) associated with OA.<h4>Methods</h4>We performed a genome-wide association study of CNV to identify potential loci that confer susceptibility to or protection from OA. CNV genotyping was conducted using NimbleGen HD2 3 × 720K comparative hybridization array and included samples from 371 OA patients and 467 healthy controls. T ...[more]